Keywords: get lost, good riddance
1. Used alone to express your frustration, irritation or anger with someone or something. You want them out of your life and to no longer bother or worry you. English = 'I'm glad its all over', 'Good riddance to that!'
2. Used alone to mean you want someone or something to stay away from you because you do not like them. Usually used talking about it (3rd person) rather than to it (2nd person) English = 'Get lost!', 'Rack off!', 'Piss off!' and so on.