1. Used to refer to people the signer is talking to. The sign is usually used immediately next to a verb and can mean the people do the action or undergo the action (i.e., another referent does the action, not the people)
2. depending on a number of factors, such as the type of verb the sign is next to and the number of other referents in the sentence. English = you. Informal English = yous, you-all.